Post by Admin on Feb 11, 2019 22:02:50 GMT
Role of Cannabinoids in Pain Management
Key Points
• Cannabinoids are pharmacological agents of endogenous (endocannabinoids), botanical (phytocannabinoids), or synthetic origin.
• Cannabinoids alleviate pain through a variety of receptor and non-receptor mechanisms including direct analgesic and anti-in fl ammatory effects,
modulatory actions on neurotransmitters, and interactions with endogenous and administered opioids.
• Cannabinoid agents are currently available in various countries for pain treatment, and even cannabinoids of
botanical origin may be approvable by FDA, although this is distinctly unlikely for smoked cannabis.
• An impressive body of literature supports cannabinoid analgesia, and recently, this has been supplemented
by an increasing number of phase I–III clinical trials.
Source: cannabiscoalition.ca/info/Russo-Hohmann-Role-of-cannabinoids-in-pain-management-2013.pdf
Key Points
• Cannabinoids are pharmacological agents of endogenous (endocannabinoids), botanical (phytocannabinoids), or synthetic origin.
• Cannabinoids alleviate pain through a variety of receptor and non-receptor mechanisms including direct analgesic and anti-in fl ammatory effects,
modulatory actions on neurotransmitters, and interactions with endogenous and administered opioids.
• Cannabinoid agents are currently available in various countries for pain treatment, and even cannabinoids of
botanical origin may be approvable by FDA, although this is distinctly unlikely for smoked cannabis.
• An impressive body of literature supports cannabinoid analgesia, and recently, this has been supplemented
by an increasing number of phase I–III clinical trials.
Source: cannabiscoalition.ca/info/Russo-Hohmann-Role-of-cannabinoids-in-pain-management-2013.pdf