Post by Admin on Feb 12, 2019 22:16:22 GMT
Oleamide is an amide of the fatty acid oleic acid. It is an endogenous substance: it occurs naturally in the body of animals. It accumulates in the cerebrospinal fluid during sleep deprivation and induces sleep in animals. It is being studied as a potential medical treatment for mood and sleep disorders, and cannabinoid-regulated depression.
The mechanism of action of oleamide's sleep inducing effects is an area of current research. It is likely that oleamide interacts with multiple neurotransmitter systems. Oleamide is structurally related to the endogenous cannabinoid anandamide, and has the ability to bind to the CB1 receptor as a full agonist.
Metabolite Description from Human Metabolome Database (HMDB)
Oleamide is a fatty amide derived from oleic acid. It has a role as a human metabolite and a plant metabolite.
Ontology Summary from ChEBI
Source: pubchem.ncbi.nlm.nih.gov/compound/Oleamide#section=Top
