Post by Admin on Nov 14, 2018 6:44:03 GMT
THE PHARMACOLOGICAL ACTIVITY OF CANNABINOL AND ITS MAJOR METABOLITE, 11-HYDROXYCANNABINOL
The pharmacological effects (catalepsy, hypothermia, pentobarbitalinduced sleep prolongation and effect on locomotor activity) of cannabinol and its major metabolite, 11-hydroxycannabinol were studied in mice. 11-Hydroxycannabinol was more potent than cannabinol in the pharmacological indices examined. The results indicate that 11-hydroxycannabinol can be categorized as an active metabolite of cannabinol.
Source
The pharmacological effects (catalepsy, hypothermia, pentobarbitalinduced sleep prolongation and effect on locomotor activity) of cannabinol and its major metabolite, 11-hydroxycannabinol were studied in mice. 11-Hydroxycannabinol was more potent than cannabinol in the pharmacological indices examined. The results indicate that 11-hydroxycannabinol can be categorized as an active metabolite of cannabinol.
Source